Email: sarah.cartmell@manchester.ac.uk

Research profile and key clinical specialties

My interdisciplinary research area focuses on orthopaedics, wound care, and early detection cancer biomarker models.

In each of these approaches I utilise biomaterials as a scaffold for a tissue engineering approach or by itself as an acellular approach to treat tissue injuries.

I have led the development of a variety of different bioreactors for such purposes, including a bioreactor that has capability of growing a bone/cartilage plug, and an electrical bioreactor that can apply physiologically relevant electrical stimuli to cells/tissue.

I also have a research interest in the development of X-ray imaging techniques for tissues. 

Two key publications

• Balint, R., Cassidy, N.J., Cartmell, S.H. (2014) Conductive Polymers: Towards a Smart Biomaterial for Tissue Engineering Acta Biomaterialia 10(6) 2341-2353.
• Juan Shong Khaw, Ruikang Xue, Nigel Cassidy, Sarah H Cartmell “Electrical Stimulation of Titanium to Promote Stem Cell Orientation, Elongation and Osteogenesis” 2021 accepted for publication in Acta Biomaterialia

Possible PhD projects

• Tendon repair products
• Mechanical force for human mesenchymal stem cell differentiation
• Co-culture bioreactor design for osteochondral tissue
• Electrical stimulation to influence stem cell proliferation and differentiation for tissue engineering

More information

My research group currently has 20 members with two PDRAs and 18 PhD students.

I am Head of The Department of Materials and President of the Tissue and Cell Engineering Society in the UK.

Keywords: orthopaedics, wound care, cancer, biomaterials, bone, cartilage, bioreactors, tissue, Sarah, Cartmell, Manchester

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Email: sarah.cartmell@manchester.ac.uk

Research profile and key clinical specialties

My interdisciplinary research area focuses on orthopaedics, wound care, and early detection cancer biomarker models.

In each of these approaches I utilise biomaterials as a scaffold for a tissue engineering approach or by itself as an acellular approach to treat tissue injuries.

I have led the development of a variety of different bioreactors for such purposes, including a bioreactor that has capability of growing a bone/cartilage plug, and an electrical bioreactor that can apply physiologically relevant electrical stimuli to cells/tissue.

I also have a research interest in the development of X-ray imaging techniques for tissues. 

Two key publications

• Balint, R., Cassidy, N.J., Cartmell, S.H. (2014) Conductive Polymers: Towards a Smart Biomaterial for Tissue Engineering Acta Biomaterialia 10(6) 2341-2353.
• Juan Shong Khaw, Ruikang Xue, Nigel Cassidy, Sarah H Cartmell “Electrical Stimulation of Titanium to Promote Stem Cell Orientation, Elongation and Osteogenesis” 2021 accepted for publication in Acta Biomaterialia

Possible PhD projects

• Tendon repair products
• Mechanical force for human mesenchymal stem cell differentiation
• Co-culture bioreactor design for osteochondral tissue
• Electrical stimulation to influence stem cell proliferation and differentiation for tissue engineering

More information

My research group currently has 20 members with two PDRAs and 18 PhD students.

I am Head of The Department of Materials and President of the Tissue and Cell Engineering Society in the UK.

Keywords: orthopaedics, wound care, cancer, biomaterials, bone, cartilage, bioreactors, tissue, Sarah, Cartmell, Manchester

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