Dr Maria Fragiadaki

by | 26 Jul 2022 | Sheffield, Supervisors | 0 comments

Email: m.fragiadaki@sheffield.ac.uk

Research profile and key clinical specialties

Chronic kidney disease is an area of unmet clinic need. My group uses cutting-edge technologies to understand key processes that lead to kidney failure in patients with Polycystic Kidney Disease (PKD) with a focus on inflammation, DNA damage and proliferation.

We aim to identify and use novel RNA therapeutics for patients suffering with genetic diseases, such as those with PKD.

Two key publications

Possible PhD projects

  • Pre-clinical testing of novel RNA therapeutics to combat PKD (nanoparticle based).
  • Proteomics and single cell transcriptomics of the polycystic kidney – discovery of new therapeutic targets.
  • Hypoxia and the polycystic kidney.

More information

Our work is currently funded by UKRI via a Future Leaders Fellowship & the Academy of Medical Sciences via a Springboard award. There are opportunities to apply for funding.

Keywords: Kidney, polycystic, PKD, DNA, proliferation, proteomics, hypoxia, polycystic, Maria, Fragiadaki, Sheffield